主要研究方向:环境微生物学;合成生物技术;水污染的新型生物控制与废弃物资源化;抗生素耐药等生态风险发生与控制
博士生导师,国家基金委优青基金获得者。主要从事微生物学、合成生物技术及环境科学与工程的交叉研究工作。研究成果以第一/通讯作者在Nature Water、PNAS、Environmental Science & Technology、Environmental Microbiology和ACS Synthetic Biology等SCI期刊上,获专利转化1项。(共同)指导学校本科生队伍2次在国际遗传工程机器大赛(iGEM)中获奖。
2023年12月-至今,特任教授,中国科学技术大学
2020年10月-2023年11月,特任副研究员/副研究员,中国科学技术大学
2017年7月-2020年9月,博士后,中国科学技术大学
2012年9月-2017年6月,联合培养博士,中科院微生物所-伊利诺伊大学香槟分校(UIUC)
2009年9月-2012年8月,硕士,中科院微生物所
2005年9月-2009年6月,本科,南京农业大学
1.环境微生物学
2.合成生物技术
3.水污染的新型生物控制与废弃物资源化
4.抗生素耐药等生态风险发生与控制
国家优青(2023)
省优秀学位论文指导教师
“雄鹰”、“雏鹰”创新创业基金指导教师
Li Yang, Syed A. Hashsham, Chen Fei-Fei, Sun Hong, Tang Qiang, Yu Han-Qing, James M. Tiedje. Engineered DNA scavenger for mitigating antibiotic resistance proliferation in wastewater treatment. Nature Water. In Publication (2024)
Sun Hong, Zhou Zhen-Jie, Wen Han-Quan, Chen Fei-Fei, Pan Yuan, Tang Qiang*, Yu Han-Qing* Deciphering the roles of extracellular polymeric substances (EPS) in shaping disinfection kinetics through permanent removal via genetic disruption. Environ. Sci. Technol.58, 6552–6563 (2024)
Liang Zi-Han, Sun Hong, Li Yang, Hu Anyi, Tang Qiang*, Yu Han-Qing*. Enforcing energy consumption promotes microbial extracellular respiration for xenobiotic bioconversion. Environ. Microbiol. 25, 2943-2957 (2023)
Sun Hong, Tang Qiang*, Li Yang, Liang Zi-Han, Li Feng-He, Li Wen-Wei, and Yu Han-Qing*. Radionuclide reduction by combinatorial optimization of microbial extracellular electron transfer with a physiologically adapted regulatory platform. Environ. Sci. Technol. 57, 674–684 (2023)
Fan Yang-Yang, Tang Qiang*, Sun Hong, Yu Han-Qing*. A designed plasmid-transition strategy enables rapid construction of robust and versatile synthetic exoelectrogens for environmental applications. Environ. Microbiol. 24, 5292-5305 (2022)
Fan Yang-Yang, Tang Qiang*, Li Yang, Li Feng-He, Wu Jing-Hang, Li Wen-Wei, Yu Han-Qing*. Rapid and highly efficient genomic engineering with a novel iEditing device for programming versatile extracellular electron transfer of electroactive bacteria. Environ. Microbiol. 23, 1238-1255 (2021)
Li Feng-He, Tang Qiang*, Fan Yang-Yang, Li Yang, Li Jie, Wu Jing-Hang, Luo Chen-Fei, Sun Hong, Li Wen-Wei, and Yu Han-Qing*. Developing a population-state decision system for intelligently reprogramming extracellular electron transfer in Shewanella oneidensis. Proc. Natl. Acad. Sci. USA. 117, 23001-23010 (2020)
Li Jie, Tang Qiang*, Li Yang, Fan Yang-Yang, Li Feng-He, Wu Jing-Hang, Min Di, Li Wen-Wei, Paul K S Lam, and Yu Han-Qing*. Rediverting electron flux with an engineered CRISPR-ddAsCpf1 system to enhance the pollutant degradation capacity of Shewanella oneidensis. Environmental Science & Technology 54, 3599-3608 (2020)
Fan Yang-Yang, Tang Qiang*, Li Feng-He, Sun Hong, Min Di, Wu Jing-Hang, Li Yang, Li Wen-Wei, and Yu Han-Qing*. Enhanced bioreduction of radionuclides by driving microbial extracellular electron pumping with an engineered CRISPR platform. Environ. Sci. Technol. 55, 11997–12008 (2021)
Tang Qiang, Lu Ting*, and Liu Shuang-Jiang*. Developing a synthetic biology toolkit for Comamonas testosteroni, an emerging cellular chassis for bioremediation. ACS Synth. Biol. 7, 1753-1762 (2018)
Tang Qiang, Lou Chunbo*, Liu Shuang-Jiang*. Construction of an easy-to-use CRISPR-Cas9 system by patching a newly designed EXIT circuit. J. Biol. Eng. DOI: 10.1186/s13036-017-0072-5 (2017)