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Biosensors based on aptamers and gold nanoparticles

  • 报告地点: 中校区应用化学楼302会议室
  • 报告时间: 2023年11月20日 16:00
  • 主讲人: Juewen Liu
  • 主讲人简介:

    Juewen Liu received his Bachelor’s degree from the University of Science & Technology of China in 2000 and Ph.D. from the University of Illinois at Urbana-Champaign in 2005. He joined the University of Waterloo in 2009 and is currently a professor of chemistry. He is interested in aptamers and biosensors. He received a Fred Beamish Award (2014) and a McBryde Medal (2018) from the Canadian Society for Chemistry for his contribution in bioanalytical chemistry. He serves as a Section Editor for Biosensors & Bioelectronics, and a Contributing Editor for TrAC Trends in Analytical Chemistry. He has published over 400 papers, receiving over 40,000 citations with an H-index of 98, and is a Clarivate Highly Cited Researcher in 2022.

  • 报告题目: Biosensors based on aptamers and gold nanoparticles

Interfacing DNA with gold nanoparticles (AuNPs) has produced a diverse range of biosensors, imaging agents, drug delivery systems, and new materials. AuNPs are particularly attractive because of their low toxicity and unique optical, electric and catalytic properties. Using fluorescently labeled oligonucleotides as probes, we measured the kinetics of DNA adsorption, desorption as well as adsorption isotherm as a function of salt, pH, and temperature.